I'm trying to take skinB5 with isotretinoin. Would this be okay? SkinB5 Help Centre (HQ) May 30, 2019 01:57 Follow Since isotretinoin is a powerful prescription medicine we recommend that you speak with your doctor first before taking skinB5 Extra Strength Acne Control Vitamins. Have more questions? Submit a request 0 Comments Please sign in to leave a comment.